{"metadata":{"accession":"A0A6J1U090","id":"A0A6J1U090_9SAUR","source_organism":{"taxId":"8663","scientificName":"Notechis scutatus","fullName":"Notechis scutatus (mainland tiger snake)"},"name":"Solute carrier family 15 member 2","description":["Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Transports neutral and anionic dipeptides with a proton to peptide stoichiometry of 2:1 or 3:1. In kidney, involved in the absorption of circulating di- and tripeptides from the glomerular filtrate. Can also transport beta-lactam antibiotics, such as the aminocephalosporin cefadroxil, and other antiviral and anticancer drugs. Transports the dipeptide-like aminopeptidase inhibitor bestatin. Also able to transport carnosine. Involved in innate immunity by promoting the detection of microbial pathogens by NOD-like receptors (NLRs). Mediates transport of bacterial peptidoglycans across the plasma membrane or, in macrophages, the phagosome membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand"],"length":726,"sequence":"MDLSEKGDPKKASFLSVSAGSVSPKSVSPPEKISPGICGTHYPLSIAFIVVNEFCERFSYYGMKAVLSLYFLYFLHWDETTSTSVYHAFSSLCYFSPVIGAFIADSWLGKYKTIIYLSIVYIIGHVIKSVGAITSVGNHITHVILSMTGLSLIALGTGGIKPCVAAFGGDQFEEKHVQERNKFFSVFYLAINAGSLISTFLTPVLRGGVQCFGGDCYALAFGVPAALMIVALVVFISGNRLYKKIPPQGNILLEVCKCIVFALRNRIRNRSPEIPKREHWLDWASEKYSNQLITEVKMVTRVLFLFIPLPMFWALFEQQGSRWTLQATKMNANFERFVLQPDQMQFLNPLLILVFIPVFDFGLYPLVNLCRLNFTPIKKMATGMILASLAFAAAAIVELKLEENGMPIPVPKESYIQVLNLADSDVELTLEGYDLFRQPIKPFQDPAEYSRLILNSDQQFIQVKIQHQGLSSTYNHSIDEMSVNSLIIYKRGGNLTTNIIEDMQKKPSEGMAAVRFINTLEWDVGITLGEEEFITVNKSYGVSDYRTLPRGRYNNAKFQMKAEVSALKLGLLDFGASYTVVLTQASTEELQAWKIEDIPANNVHISWQIPQYLLMSAGEVMFSISGLAFSYSQAPVNMKSVLQAGWLLTVAFGNMIVLIVAQSAPLVQWAEFILFAMLLFIVFVIFSIMGYFYISTDPEELADKGNEHETSSNKNMIGLVTRKTKL","proteome":"UP000504612","gene":"SLC15A2","go_terms":[{"identifier":"GO:0022857","name":"transmembrane transporter activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0055085","name":"transmembrane transport","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0006857","name":"oligopeptide transport","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"ida_accession":"03980fe80fd29f5043b13de7a766dbc1745073d3","counters":{"domain_architectures":9800,"entries":10,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":1,"cdd":1,"panther":1,"pfam":1,"prosite":2,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":9800}}}