{"metadata":{"accession":"A0A6J1LEY5","id":"A0A6J1LEY5_DROHY","source_organism":{"taxId":"7224","scientificName":"Drosophila hydei","fullName":"Drosophila hydei (Fruit fly)"},"name":"Fibrinogen C-terminal domain-containing protein","description":["Lectin involved in innate immunity. Agglutinates all types of human erythrocytes, Gram-positive and Gram-negative bacteria. Has a stronger agglutinating activity towards Gram-negative bacteria than towards Gram-positive bacteria. Specifically recognizes acetyl group-containing substances on agglutinated cells. The hemagglutinating activity was inhibited by EDTA, acetyl group-containing mono- and disaccharides, N-acetyl derivatives of amino acids, other acetyl group-containing substances, propionamide and benzamide. Enhances the antimicrobial activity of big defensin against Gram-positive bacteria but not against Gram-negative bacteria"],"length":296,"sequence":"MLSRNICTIFLFVYISIAKCEDDKDGNFTVKYKNKSEIHFIMNDSNALLLQAQLEAMRLEQRNLFAELSAKVDKLMASNLLSSQFPDSCAKATAMSRRSGAYQIVIPDYSVHPFIVSCDEDTQNGGWLVILRREDGSLNFFRYWNDYKNGFGNVSGEFFIGLDKLHLLTKERNQELLISMEDFKGNKRYAKYTQFSVGSEQNLYALQTLGEYSGDAGDSLSPHLGQKFTARDRDNDNYSRNCAELYTGGWWYDKCHSSNLMGKYNDSTHGKGINWLLFSGHTASLKFVQMMIRNVQ","proteome":"UP000504633","gene":"LOC111594107","go_terms":null,"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"773c1c4bd0ba3f4a7d67718754a692a4fd7e8b22","counters":{"domain_architectures":32923,"entries":11,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"profile":1,"ssf":1,"cdd":1,"smart":1,"pfam":1,"panther":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":32923}}}