{"metadata":{"accession":"A0A6C7IED1","id":"A0A6C7IED1_SALTD","source_organism":{"taxId":"568708","scientificName":"Salmonella typhimurium (strain D23580)","fullName":"Salmonella typhimurium (strain D23580)"},"name":"Sulfite reductase [NADPH] flavoprotein alpha-component","description":["Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component"],"length":539,"sequence":"MPRVTLISASQTGNARRVAEALRDDLLAANLNVTLVNAGDYKFKQIASEKLLVIVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDTSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDVLKSRAPVAAPSQSVATGAVNDIHTSPYTKDAPLIATLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVDGKTLPLAEALEWHFELTVNTANIVENYATLTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAQALIDLLRPLTPRLYSIASAQAEVESEVHITVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRSFMQQRAAEGVEGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLSRIDLAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDARRMAADVEKALLEVIAEFGGMDLESADEYLSELRVERRYQRDVY","proteome":null,"gene":"cysJ","go_terms":[{"identifier":"GO:0010181","name":"FMN binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016491","name":"oxidoreductase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004783","name":"sulfite reductase (NADPH) activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0050660","name":"flavin adenine dinucleotide binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0000103","name":"sulfate assimilation","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0019344","name":"L-cysteine biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"a940318bfe18887bd690aa0ff414b314e8cedbe8","counters":{"domain_architectures":17636,"entries":31,"isoforms":0,"proteomes":0,"sets":4,"structures":0,"taxa":1,"dbEntries":{"ssf":3,"cathgene3d":4,"profile":2,"pfam":3,"cdd":1,"hamap":1,"ncbifam":2,"panther":1,"prints":2,"interpro":12},"proteome":0,"taxonomy":1,"similar_proteins":17636}}}