{"metadata":{"accession":"A0A5C6CJF9","id":"A0A5C6CJF9_9BACT","source_organism":{"taxId":"2528003","scientificName":"Bythopirellula polymerisocia","fullName":"Bythopirellula polymerisocia"},"name":"Multifunctional fusion protein","description":["Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)","Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate"],"length":500,"sequence":"MICVAIGRSRHKHILAEHRHLCEQGAKLVELRLDYVTSKINIRRLLAEQKDLDCKIIITCRRLEDGGKWTGSEEARQLVLREAIAEGVDYVDIEEDVAGQIPRFGKSKRIISYHNFRKTPENLRDLHRDMSKLDPDIIKITTMANDPHDNLRMLEMMQESEIPTVGICMGDVGTPSRILAAKFGAPFTYATFHHERTLAPGQLSFQQMTDIYRYEKIGPDTEVYGVIADPIGHSLSPHVHNAAFEARGIDAVYCPFRVPSDGLEQFMIDAPRLGIKGLSVTIPHKEAIAKHLTKVDPAVKSIAAVNTVVFDGSEVIGYNTDYNSAMDCLEHSMGGIGTKPSPLRNQRALVLGAGGVARPIVYGLKSRGAFVTIASRTKQRADRLADAFDCKAIDWESRQRAQCDILINCTPIGMHPNVDESPVSKTFLKPSILVFDTVYNPESTLLVKDARARNCEAITGVEMFVRQARLQFYLFTKQEAPPGLMRDVLKKAIGPIGIGR","proteome":"UP000318437","gene":"aroE","go_terms":[{"identifier":"GO:0003855","name":"3-dehydroquinate dehydratase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004764","name":"shikimate 3-dehydrogenase (NADP+) activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0050661","name":"NADP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0019632","name":"shikimate metabolic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"de8c0366fbca03516e516c1ed540c74266342fd6","counters":{"domain_architectures":1352,"entries":26,"isoforms":0,"proteomes":1,"sets":5,"structures":0,"taxa":1,"dbEntries":{"ssf":3,"cdd":2,"cathgene3d":3,"pfam":4,"ncbifam":2,"hamap":2,"panther":1,"interpro":9},"proteome":1,"taxonomy":1,"similar_proteins":1352}}}