{"metadata":{"accession":"A0A3P8XB92","id":"A0A3P8XB92_ESOLU","source_organism":{"taxId":"8010","scientificName":"Esox lucius","fullName":"Esox lucius (Northern pike)"},"name":"Derlin","description":["Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome"],"length":244,"sequence":"MAQSFTQEYFQIPSVTRAYTTACVLTTAAVQLEVITPFQLYFNPDLIIRRYQIWRLITNFLFFGSLGFSFLFNIIFLYRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLFGLFANLFFLGQAFTIMLVYVWSRRNPYIRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIVVDLLGIGVGHIYYFLEDVFPNQPGGRKLLITPELLRTVFDTPEDDPGYSPLTEEPAGEFWQDRGVDGGEPNDQGQ","proteome":"UP000265140","gene":"DERL2","go_terms":null,"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"5e289f64f63688d2c84bfacb1b0e28f6212c66ce","counters":{"domain_architectures":11300,"entries":5,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"panther":1,"pfam":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":11300}}}