{"metadata":{"accession":"A0A2Y9DDR4","id":"A0A2Y9DDR4_TRIMA","source_organism":{"taxId":"127582","scientificName":"Trichechus manatus latirostris","fullName":"Trichechus manatus latirostris (Florida manatee)"},"name":"Polypyrimidine tract-binding protein 3","description":["RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes Fas exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U)"],"length":524,"sequence":"MNNSTSAPGVYANGNDNKKFKGDRPPCSPSRVLHLRKIPNDVTEAEVISLGLPFGRVTNLLILKGKSQAFLEMASEEAAVTMVNYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAISAAQPGSLALSGAPTNEGTVLSGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYARMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFGPAIGFPQATGLSVSAVPGALGPLAIASSAVTGRMTIPGAGGIPGNSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFTDAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALVELHNHDLGENHHLRVSFSKSTI","proteome":"UP000248480","gene":"PTBP3","go_terms":[{"identifier":"GO:0003676","name":"nucleic acid binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003723","name":"RNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006397","name":"mRNA processing","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005634","name":"nucleus","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"41e57ad083d6a04f9c691de8c8f2fc512151e2c2","counters":{"domain_architectures":5202,"entries":18,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"cdd":2,"profile":1,"smart":1,"pfam":3,"panther":1,"ncbifam":1,"interpro":7},"proteome":1,"taxonomy":1,"similar_proteins":5202}}}