{"metadata":{"accession":"A0A2R8ZB90","id":"A0A2R8ZB90_PANPA","source_organism":{"taxId":"9597","scientificName":"Pan paniscus","fullName":"Pan paniscus (Pygmy chimpanzee)"},"name":"Diablo IAP-binding mitochondrial protein","description":["Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/BRUCE by inhibiting its binding to caspases"],"length":186,"sequence":"MKSDFYFQKSEPHSLSSEALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITTRNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED","proteome":"UP000240080","gene":"DIABLO","go_terms":[{"identifier":"GO:0006915","name":"apoptotic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005739","name":"mitochondrion","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"f4a814e5ebc7e419702679c57fa452279ab8112d","counters":{"domain_architectures":1425,"entries":6,"isoforms":0,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"pfam":1,"ssf":1,"panther":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":1425}}}