{"metadata":{"accession":"A0A2D0T4G3","id":"A0A2D0T4G3_ICTPU","source_organism":{"taxId":"7998","scientificName":"Ictalurus punctatus","fullName":"Ictalurus punctatus (Channel catfish)"},"name":"Ankyrin repeat domain-containing protein 16","description":["Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides"],"length":370,"sequence":"MSDENIYKLLIKLTQDGHLCKIKSQIEETSEIKQSMNAHVGKSGDTLLHYAARHGHLDIVKYFVEDLNVDVELHNNDYKRALHEASSMCHEQCVRYLLDKGAKIDCLKKADWTPLMMACTRRNLEVIRVLLDHGADPTLQNKDGWNSFHIACREGDPAVIEHLLHIRPEVWRTESKTRRTPLHTAAMHGCLEVVKILLERCDYKPDEKDSCGVTPFMDAVRNGHLGVAKLLLDKHQACPTAVDILGAQPLHQASVTAQEEALRFLVHELSVDVNVRATALELTALHYAAKEGHTDTIKTLLQLGADLHARDKKGRSALHMACIGQHAITARALLQLGLTDTEDSTGTTARQHAKNPDMTRVFEMPEEPEP","proteome":"UP000221080","gene":"ankrd16","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"f196c91e450d0b43eaba86aaef2032b0e3aa4dcd","counters":{"domain_architectures":346,"entries":12,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"pfam":2,"ssf":1,"profile":2,"smart":1,"panther":1,"prints":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":346}}}