{"metadata":{"accession":"A0A1R4EPS2","id":"A0A1R4EPS2_9MICC","source_organism":{"taxId":"71253","scientificName":"Arthrobacter rhombi","fullName":"Arthrobacter rhombi"},"name":"Tryptophan 2,3-dioxygenase","description":["Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety"],"length":296,"sequence":"MSCPYSQDTPETPGTDTGERDIEETVRTDFRNEMSYGGYLDLDKVLHAQHPHSNPEHHDELLFIIQHQTSELWLKLVLHELVEARRLMDADDLGKALKCLARVKHIQKVLTDQWSVLATLTPREYAQFRDTLGSASGFQSWQYRAVEFILGNKHRGMLKVFESHPEAHAMLSQLLEEPTVYDAFLAALSRAGYPISEEILHRDFSKAWVLHEELIPVFKEIYETEETRWGFYQACEDLVDLEDNFQAWRFRHLRTVQRTIGFKRGTGGSSGVDFLRRALDLTFFPELYAVRTEIGN","proteome":"UP000195913","gene":"kynA","go_terms":[{"identifier":"GO:0020037","name":"heme binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0046872","name":"metal ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0019441","name":"L-tryptophan catabolic process to L-kynurenine","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0004833","name":"L-tryptophan 2,3-dioxygenase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"aff128451d43e340f1379ffdcbc3092f5b264d66","counters":{"domain_architectures":4439,"entries":9,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"panther":1,"pfam":1,"hamap":1,"ncbifam":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":4439}}}