{"metadata":{"accession":"A0A096MY53","id":"A0A096MY53_PAPAN","source_organism":{"taxId":"9555","scientificName":"Papio anubis","fullName":"Papio anubis (Olive baboon)"},"name":"Inosine-5'-monophosphate dehydrogenase","description":["Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors"],"length":513,"sequence":"MNYLISGGTLYVPEDGLTAQQLFASADGLTYDDFLILPGFIDFLTGEVDLTSALTRKITLKTPLISFPTDTVTEADMAIAMALMGGIGFIHHNCTPEFQANKVQKVKKFEQGFITDPVVLSPSHTVRDVLEAKVRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIKLVVAPAGVTFEEANEILKRSKKGKLPVVNDHDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAVVGTREDDKFRLDLLTQAGVDVIVLDSSQGNLVYQIAMVHYTKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLHVGMGCGSTCITPEVMACGRIHGSAVYKVAEYARRFGVPIIADGGIQTLGHVVKALALGASTVMMGSLLAATTEASAEYFFSDGVPLKKYQGMGSLDAMEKSSSSQKRYFSERDKVKFAQSISGSIQDKGFIQKFVPYLIAGIQHSCQDIGARSLSVLRSMMYSGELKFEKRTVSAQMEGGVHGLHSYEKRLY","proteome":"UP000028761","gene":"IMPDH","go_terms":[{"identifier":"GO:0003824","name":"catalytic activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003938","name":"IMP dehydrogenase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006164","name":"purine nucleotide biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"9a01abf0d371224a404878e839c2974d8a828f12","counters":{"domain_architectures":30944,"entries":17,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"smart":2,"cdd":2,"pfam":2,"profile":1,"panther":1,"pirsf":1,"ncbifam":1,"hamap":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":30944}}}