{"metadata":{"accession":"PF12704","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR025857","hierarchy":null,"name":{"name":"MacB-like periplasmic core domain","short":"MacB_PCD"},"description":[{"text":"<p>This family represents the periplasmic core domain found in a variety of ABC transporters. The structure of this family has been solved for the MacB protein [[cite:PUB00052047]]. Some structural similarity was found to the periplasmic domain of the AcrB multidrug efflux transporter.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00052047":{"PMID":19432486,"ISBN":null,"volume":"48","issue":"23","year":2009,"title":"Crystal structure of the periplasmic region of MacB, a noncanonic ABC transporter.","URL":null,"raw_pages":"5218-25","medline_journal":"Biochemistry","ISO_journal":"Biochemistry","authors":["Xu Y","Sim SH","Nam KH","Jin XL","Kim HM","Hwang KY","Lee K","Ha NC."],"DOI_URL":"http://dx.doi.org/10.1021/bi900415t"}},"set_info":{"accession":"CL0199","name":"DPBB"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":82,"interactions":0,"matches":138882,"pathways":0,"proteins":119884,"proteomes":16875,"sets":1,"structural_models":{"alphafold":90889,"bfvd":0},"structures":38,"taxa":29068},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":386,"alignment:full":53250},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"5lj8","name":"Structure of the E. coli MacB periplasmic domain (P21)"}}}