{"metadata":{"accession":"PF02769","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR010918","hierarchy":null,"name":{"name":"AIR synthase related protein, C-terminal domain","short":"AIRS_C"},"description":[{"text":"<p>This family includes Hydrogen expression/formation protein  HypE [swissprot:P24193], AIR synthases [swissprot:P08178] [ec:6.3.3.1], FGAM synthase [swissprot:P35852] [ec:6.3.5.3] and selenide, water dikinase [swissprot:P16456] [ec:2.7.9.3]. The function of the C-terminal domain of AIR synthase is unclear, but the cleft formed between N and C domains is postulated as a sulphate binding site [[cite:PUB00014643]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00014643":{"PMID":10508786,"ISBN":null,"volume":"7","issue":"9","year":1999,"title":"X-ray crystal structure of aminoimidazole ribonucleotide synthetase (PurM), from the Escherichia coli purine biosynthetic pathway at 2.5 A resolution.","URL":null,"raw_pages":"1155-66","medline_journal":"Structure","ISO_journal":"Structure","authors":["Li C","Kappock TJ","Stubbe J","Weaver TM","Ealick SE."],"DOI_URL":"http://dx.doi.org/10.1016/S0969-2126(99)80182-8"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":452,"interactions":0,"matches":128844,"pathways":0,"proteins":101851,"proteomes":20738,"sets":0,"structural_models":{"alphafold":71009,"bfvd":11},"structures":79,"taxa":38613},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":119,"alignment:full":49709},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"2zau","name":"Crystal structure of an N-terminally truncated selenophosphate synthetase from Aquifex aeolicus"}}}