This is a family of plant transcription factors with various roles in development, the aligned region corresponds the B3 DNA binding domain as described in [[cite:PUB00008122]] this domain is found in VP1/AB13 transcription factors [[cite:PUB00019193]]. Some proteins also have a second AP2 DNA binding domain [pfam:PF00847] such as RAV1 [swissprot:Q9ZWM9] [[cite:PUB00008122]]. DNA binding activity was demonstrated by [[cite:PUB00018332]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"B3_domain","extract":"The B3 DNA binding domain (DBD) is a highly conserved domain found exclusively in transcription factors combined with other domains. It consists of 100-120 residues, includes seven beta strands and two alpha helices that form a DNA-binding pseudobarrel protein fold ; it interacts with the major groove of DNA.
","thumbnail":null}],"literature":{"PUB00019193":{"PMID":9188533,"ISBN":null,"volume":"276","issue":"5320","year":1997,"title":"ARF1, a transcription factor that binds to auxin response elements.","URL":null,"raw_pages":"1865-8","medline_journal":"Science","ISO_journal":"Science","authors":["Ulmasov T","Hagen G","Guilfoyle TJ."],"DOI_URL":"http://dx.doi.org/10.1126/science.276.5320.1865"},"PUB00008122":{"PMID":9862967,"ISBN":null,"volume":"27","issue":"2","year":1999,"title":"RAV1, a novel DNA-binding protein, binds to bipartite recognition sequence through two distinct DNA-binding domains uniquely found in higher plants.","URL":null,"raw_pages":"470-8","medline_journal":"Nucleic Acids Res","ISO_journal":"Nucleic Acids Res.","authors":["Kagaya Y","Ohmiya K","Hattori T."],"DOI_URL":"http://dx.doi.org/10.1093/nar/27.2.470"},"PUB00018332":{"PMID":9165754,"ISBN":null,"volume":"9","issue":"5","year":1997,"title":"The conserved B3 domain of VIVIPAROUS1 has a cooperative DNA binding activity.","URL":null,"raw_pages":"799-807","medline_journal":"Plant Cell","ISO_journal":"Plant Cell","authors":["Suzuki M","Kao CY","McCarty DR."],"DOI_URL":"http://dx.doi.org/10.1105/tpc.9.5.799"}},"set_info":{"accession":"CL0405","name":"DNA_b-psBarrel"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":769,"interactions":0,"matches":66564,"pathways":0,"proteins":50203,"proteomes":406,"sets":1,"structural_models":{"alphafold":43339,"bfvd":0},"structures":21,"taxa":1472},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":87,"alignment:full":37961},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"5os9","name":"Structure of the B3 DNA-Binding Domain of NGA1"}}}