{"metadata":{"accession":"PF01730","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR002639","hierarchy":null,"name":{"name":"UreF","short":"UreF"},"description":[{"text":"<p>This family consists of the Urease accessory protein  UreF. The urease enzyme (urea amidohydrolase) hydrolyses urea into ammonia and carbamic acid [[cite:PUB00002304]].  UreF is proposed to modulate the activation process of urease by eliminating the binding of nickel irons to  noncarbamylated protein [[cite:PUB00002303]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00002304":{"PMID":8550495,"ISBN":null,"volume":"178","issue":"3","year":1996,"title":"Organization of Ureaplasma urealyticum urease gene cluster and expression in a suppressor strain of Escherichia coli.","URL":null,"raw_pages":"647-55","medline_journal":"J Bacteriol","ISO_journal":"J. Bacteriol.","authors":["Neyrolles O","Ferris S","Behbahani N","Montagnier L","Blanchard A."],"DOI_URL":"http://ukpmc.ac.uk/picrender.cgi?tool=EBI&pubmedid=8550495&action=stream&blobtype=pdf"},"PUB00002303":{"PMID":8808930,"ISBN":null,"volume":"178","issue":"18","year":1996,"title":"Purification and activation properties of UreD-UreF-urease apoprotein complexes.","URL":null,"raw_pages":"5417-21","medline_journal":"J Bacteriol","ISO_journal":"J. Bacteriol.","authors":["Moncrief MB","Hausinger RP."],"DOI_URL":"http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=EBI&pubmedid=8808930"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":43,"interactions":0,"matches":13164,"pathways":0,"proteins":13140,"proteomes":8731,"sets":0,"structural_models":{"alphafold":9881,"bfvd":0},"structures":7,"taxa":15380},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":235,"alignment:full":5234},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"3o1q","name":"Native Crystal Structure of Helicobacter pylori Urease Accessory Protein UreF"}}}