{"metadata":{"accession":"IPR056779","entry_id":null,"type":"domain","go_terms":null,"source_database":"interpro","member_databases":{"pfam":{"PF25038":"Csf1 family C-terminal region"}},"integrated":null,"hierarchy":{"accession":"IPR056779","name":"Csf1, C-terminal region","type":"Domain","children":[]},"name":{"name":"Csf1, C-terminal region","short":"Csf1_C"},"description":[{"text":"<p>This entry represents the C-terminal region of Csf1.</p>","llm":false,"checked":false,"updated":false},{"text":"<p>This entry includes Csf1 protein from yeast, which is the orthologue of human BLTP1. These are tube-forming lipid transport proteins which provide phosphatidylethanolamine for glycosylphosphatidylinositol (GPI) anchor synthesis in the endoplasmic reticulum [[cite:PUB00101862]]. They belong to the repeating β-groove (RBG) superfamily which are conserved lipid transfer proteins containing long hydrophobic grooves consisting of multiple repeating modules made of five β-sheets followed by a loop [[cite:PUB00101861]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00101861":{"PMID":35491307,"ISBN":null,"volume":"32","issue":"11","year":2022,"title":"A novel superfamily of bridge-like lipid transfer proteins.","URL":null,"raw_pages":"962-974","medline_journal":"Trends Cell Biol","ISO_journal":"Trends Cell Biol","authors":["Neuman SD","Levine TP","Bashirullah A."],"DOI_URL":null},"PUB00101862":{"PMID":35015055,"ISBN":null,"volume":"221","issue":"3","year":2022,"title":"Vps13-like proteins provide phosphatidylethanolamine for GPI anchor synthesis in the ER.","URL":null,"raw_pages":"e202111095","medline_journal":"J Cell Biol","ISO_journal":"J Cell Biol","authors":["Toulmay A","Whittle FB","Yang J","Bai X","Diarra J","Banerjee S","Levine TP","Golden A","Prinz WA."],"DOI_URL":null},"PUB00070565":{"PMID":10781556,"ISBN":null,"volume":"182","issue":"10","year":2000,"title":"Cloning and characterization of the CSF1 gene of Saccharomyces cerevisiae, which is required for nutrient uptake at low temperature.","URL":null,"raw_pages":"2865-8","medline_journal":"J Bacteriol","ISO_journal":"J. Bacteriol.","authors":["Tokai M","Kawasaki H","Kikuchi Y","Ouchi K."],"DOI_URL":"http://dx.doi.org/10.1128/JB.182.10.2865-2868.2000"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":28,"interactions":0,"matches":1539,"pathways":0,"proteins":1304,"proteomes":1041,"sets":0,"structural_models":{"alphafold":37,"bfvd":0},"structures":0,"taxa":2186},"entry_annotations":{"alignment:seed":2,"alignment:full":1016},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}