UBAC1, UBA domain 1 (IPR041926)

Short name: UBA1_UBAC1

Overlapping homologous superfamilies

Domain relationships


UBAC1 (also known as KPC2, or glialblastoma cell differentiation-related protein 1) is one of two subunits of Kip1 ubiquitination-promoting complex (KPC), a novel E3 ubiquitin-protein ligase that also contains KPC1 subunit and regulates the ubiquitin-dependent degradation of the cyclin-dependent kinase (CDK) inhibitor p27 at G1 phase. KPC2 contains a ubiquitin-like (UBL) domain and two ubiquitin-associated (UBA) domains [PMID: 15531880, PMID: 15746103].

This entry represents the first UBA domain.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.