Domain

IKBKB, scaffold dimerization domain (IPR041185)

Short name: IKBKB_SDD

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This is the C-terminal scaffold dimerization domain (SDD) found in inhibitor of nuclear factor kappa-B kinase subunit beta (IKBKB) [PMID: 23792959]. IKBKB is one of the core component of IKB kinases (IKK), which is an enzyme that quickly becomes active in response to diverse stresses. The SDD consists primarily of two long alpha-helices [PMID: 23776406]. This domain can also be found in inhibitor of nuclear factor kappa-B kinase subunit alpha (IKKA).

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam