Importin beta family (IPR040122)

Short name: Importin_beta

Overlapping homologous superfamilies

Family relationships


This family consists of the karyopherins importin-beta and transportin. Importin subunit beta-1 forms a complex with an importin alpha subunit. The importin complex is required for nuclear protein import. Importins bind to NLSs in their protein cargos to transport them through the nuclear pore into the nucleus [PMID: 26173234].

Transportin-1 and -2 also function in nuclear import [PMID: 24780099]. Transportin-1 was first identified as the import factor for the heterogeneous ribonucleoprotein A1 (hnRNP A1) [PMID: 9298975].

GO terms

Biological Process

GO:0006606 protein import into nucleus

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.