Family

Rho guanine nucleotide exchange factor 10/17 (IPR039919)

Short name: ARHGEF10/ARHGEF17

Overlapping homologous superfamilies

None.

Family relationships

Description

This entry includes Rho guanine nucleotide exchange factors 10 and 17.

ARHGEF10 is a Rho guanine nucleotide exchange factor that may play a role in developmental myelination of peripheral nerves [PMID: 14508709]. It was found to regulate mitotic spindle formation and play a role in the regulation of the cell division cycle [PMID: 19635168].

ARHGEF17 is a guanine nucleotide exchange for for RhoA GTPases; it contains a Dbl homology (DH) domain but lacks the typical pleckstrin homology domain [PMID: 12071859].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005089 Rho guanyl-nucleotide exchange factor activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER