Fetal and adult testis-expressed transcript protein (IPR039153)

Short name: FATE1

Overlapping homologous superfamilies


Family relationships



FATE1 is a member of the Miff protein family, whose members are involved in the control of mitochondrial and peroxisomal fission. It is localized in mitochondria associated ER membranes (MAM) and is implicated in the regulation of Ca2+ and drug-dependent apoptosis in cancer cells by modulating ER-mitochondria distance [PMID: 27402544]. Homologues are found only in chordates.

GO terms

Biological Process

GO:0042981 regulation of apoptotic process

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.