Homologous Superfamily

Rnp2-like domain superfamily (IPR038085)

Short name: Rnp2-like_sf

Overlapping entries


This superfamily contains proteins found in some eukaryotes and archaebacteria that are related to yeast ribonuclease P (Rnp). This enzyme is essential for tRNA processing generating 5'-termini of mature tRNA molecules [PMID: 7731988]. Human tRNA processing enzyme ribonuclease P (RNase P) consists of an RNA molecule associated with at least eight protein subunits, hPop1, Rpp14, Rpp20, Rpp25, Rpp29, Rpp30, Rpp38, and Rpp40 [PMID: 10024167].

The structure of Rnp2 (ribonuclease P protein component 2) has a ferrodoxin-like fold composed of an alpha-beta sandwich with antiparallel beta-sheet and contains an extra C-terminal helix.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.