RACK7, Bromo domain (IPR037967)

Short name: RACK7_Bromo_dom

Overlapping homologous superfamilies

Domain relationships

  • Bromodomain (IPR001487)
    • RACK7, Bromo domain (IPR037967)


RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumour suppressor gene. It shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular proliferation [PMID: 12948759]. RACK7 functions together with KDM5C as an enhancer 'brake' to ensure appropriate enhancer activity [PMID: 27058665].

This entry represents the bromodomain of RACK7. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine [PMID: 11911891].

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.