Domain

RACK7, Bromo domain (IPR037967)

Short name: RACK7_Bromo_dom

Overlapping homologous superfamilies

Domain relationships

  • Bromodomain (IPR001487)
    • RACK7, Bromo domain (IPR037967)

Description

RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumour suppressor gene. It shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular proliferation [PMID: 12948759]. RACK7 functions together with KDM5C as an enhancer 'brake' to ensure appropriate enhancer activity [PMID: 27058665].

This entry represents the bromodomain of RACK7. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine [PMID: 11911891].

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD