Family

1,4-alpha-glucan-branching enzyme (IPR037439)

Short name: Branching_enzy

Overlapping homologous superfamilies

Family relationships

Description

This entry consists of glycogen branching enzyme GlgB from bacteria and GBE1 from eukaryotes, which are responsible for the transfer of chains of alpha(1,4)-linked glucosyl residues to other similar chains (in new alpha-(1,6) linkages) in the biosynthesis of glycogen [PMID: 7862674]. GlgB is responsible for the degree of alpha(1,6) branch linkages found in polysaccharides [PMID: 2959476]. GBE1 is required for normal glycogen accumulation in animals [PMID: 8463281, PMID: 26199317]. Deficiency in GBE1 results in glycogen storage disease type IV [PMID: 8613547].

GO terms

Biological Process

GO:0005978 glycogen biosynthetic process

Molecular Function

GO:0003844 1,4-alpha-glucan branching enzyme activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF
PANTHER