Homologous Superfamily

Elafin-like superfamily (IPR036645)

Short name: Elafin-like_sf

Overlapping entries


Elafin is an elastase inhibitor. It contains a flat core and a flexible N-terminal extremity, the three-dimensional structure is formed by a central twisted beta-hairpin accompanied by two external segments linked by the proteinase binding loop [PMID: 9171290]. This superfamily describes the C-terminal four-disulphide core or Whey Acidic Protein (WAP) domain, which harbours a functional motif involved in binding of proteinases and possibly other proteins [PMID: 10359639].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.