Homologous Superfamily

Dehydroquinase, class II superfamily (IPR036441)

Short name: DHquinase_II_sf

Overlapping entries


3-dehydroquinate dehydratase (EC:, or dehydroquinase, catalyzes the conversion of 3-dehydroquinate into 3-dehydroshikimate. It is the third step in the shikimate pathway for the biosynthesis of aromatic amino acids from chorismate. Two classes of dehydroquinases exist, known as types I and II. Class-II enzymes are homododecameric enzymes of about 17 kDa. They are found in some bacteria such as actinomycetales [PMID: 1910148, PMID: 8170389] and some fungi where they act in a catabolic pathway that allows the use of quinic acid as a carbon source.

The dehydroquinase structure has a flavodoxin-like fold, which is composed of three layers (alpha/beta/alpha) with parallel beta-sheet of five strands.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003855 3-dehydroquinate dehydratase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.