Homologous Superfamily

Glutamyl-tRNA reductase, N-terminal domain superfamily (IPR036343)

Short name: GluRdtase_N_sf

Overlapping entries


This entry represents the N-terminal domain superfamily of glutamyl-tRNA reductase (EC:, which reduces glutamyl-tRNA to glutamate-1-semialdehyde during the first stage of tetrapyrrole biosynthesis by the C5 pathway [PMID: 11215515, PMID: 1502723]. The enzyme requires NADPH as a cofactor. This domain has a Ferredoxin-like fold, which consits of an alpha+beta sandwich with antiparallel beta-sheet.

GO terms

Biological Process

GO:0055114 oxidation-reduction process
GO:0033014 tetrapyrrole biosynthetic process

Molecular Function

GO:0050661 NADP binding
GO:0008883 glutamyl-tRNA reductase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.