Homologous Superfamily

Dbl homology (DH) domain superfamily (IPR035899)

Short name: DBL_dom_sf

Overlapping entries


The DH domain is composed of 11 alpha helices that are folded into a flattened, elongated alpha-helix bundle in which two of the three conserved regions, conserved region 1 (CR1) and conserved region 3 (CR3), are exposed near the centre of one surface. CR1 and CR3, together with a part of alpha-6 and the DH/PH junction site, constitute the Rho GTPase interacting pocket [PMID: 9846881, PMID: 9790532].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.