Netrin-4, NTR domain (IPR035811)

Short name: Netrin-4_NTR

Overlapping homologous superfamilies

Domain relationships


This is the C-terminal netrin (NTR) domain of netrin-4 (beta-netrin) [PMID: 10452607]. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration during neural development. Netrin-4 is a basement membrane component that is important in neural, kidney and vascular development [PMID: 11038171]. It may also be involved in regulating the outgrowth and shape of epithelial cells during lung branching morphogenesis [PMID: 15186747].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.