Fibronectin type III and SPRY containing 1, PRY/SPRY domain (IPR035742)

Short name: SPRY/PRY_FSD1

Overlapping homologous superfamilies

Domain relationships


This domain is part of the fibronectin type III and SPRY domain containing 1 (FSD1) and FSD1-like (FSD1L) proteins. These are centrosome-associated proteins that are characterized by an N-terminal coiled-coil region downstream of B-box (BBC) domain, a central fibronectin type III (FN3) domain, and C-terminal PRY/SPRY domain [PMID: 11267680]. The FSD1 protein associates with a subset of microtubules and may be involved in the stability and organization of microtubules during cytokinesis [PMID: 12445389, PMID: 12154070].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.