Homologous Superfamily

Invertase/pectin methylesterase inhibitor domain superfamily (IPR035513)

Short name: Invertase/methylesterase_inhib

Overlapping entries


This superfamily represents pectin methylesterases (PMEs) and invertases complex, the uncharacterized protein Os08g from Oryza sativa subsp. japonica (Rice) and the uncharacterized vacuolar membrane protein YNR061C from Saccharomyces cerevisiae (Baker's yeast).

This domain inhibits pectin methylesterases (PMEs) and invertases through formation of a non-covalent 1:1 complex [PMID: 8521860]. It has been implicated in the regulation of fruit development, carbohydrate metabolism and cell wall extension [PMID: 10880981]. It may also be involved in inhibiting microbial pathogen PMEs. It has been observed that it is often expressed as a large inactive preprotein [PMID: 8521860]. It is also found at the N-termini of PMEs, suggesting that both PMEs and their inhibitor are expressed as a single polyprotein and subsequently processed. It has two disulphide bridges and is mainly alpha-helical [PMID: 10880981].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.