Domain

GlmS/AgaS, SIS domain 1 (IPR035466)

Short name: GlmS/AgaS_SIS

Domain relationships

Description

AgaS is a putative isomerase in Escherichia coli [PMID: 10931310]. It is similar to glucosamine-6-phosphate synthases (GlmS), which catalyzes the first step in hexosamine metabolism. GlmS converts fructose 6-phosphate into glucosamine 6-phosphate using glutamine as nitrogen source [PMID: 20709015].

GlmS contains a N-terminal glutaminase domain and two C-terminal SIS (Sugar ISomerase) domains. This domain is the first SIS domain found in GlmS and AgaS.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD