Acetyl-CoA carboxylase (IPR034733)

Short name: AcCoA_carboxyl

Overlapping homologous superfamilies


Domain relationships



All of the members in this family are biotin dependent carboxylases [PMID: 8102604, PMID: 8366018]. The carboxyl transferase domain carries out the following reaction; transcarboxylation from biotin to an acceptor molecule. There are two recognised types of carboxyl transferase. One of them uses acyl-CoA and the other uses 2-oxoacid as the acceptor molecule of carbon dioxide. All of the members in this family utilise acyl-CoA as the acceptor molecule.

In bacteria, the acetyl coenzyme A carboxylase (ACC) is a complex consisting of two subunits: alpha and beta. This domain also recognizes the bacterial ACC beta-subunit.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.