Retinitis pigmentosa 9 protein (IPR034585)

Short name: PAP-1

Overlapping homologous superfamilies


Family relationships



PAP-1 (for Pim-1-associated protein) is thought to be a target for Pim-1 kinase [PMID: 10931201]. It has been implicated as the defective gene in RP9, one type of autosomal dominant retinitis pigmentosa [PMID: 12032732]. PAP-1 has a role in pre-mRNA splicing and this activity is dependent on its phosphorylation state [PMID: 15474994]. PAP-1 interacts with Prp3p; both were found to be components of the U4/U6.U5-tri-snRNP complex, one form of the spliceosome [PMID: 15541726].

GO terms

Biological Process

GO:0008380 RNA splicing

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.