Carbamoyl-phosphate synthase large chain, methylglyoxal synthase-like domain (IPR033937)

Short name: MGS_CPS_CarB

Overlapping homologous superfamilies

Domain relationships


This entry represents the methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways responsible for the synthesis of pyrimidine nucleotides or arginine. The MGS-like domain is the C-terminal domain of CarB and appears to play a regulatory role in CPS function by binding allosteric effector molecules, including UMP and ornithine [PMID: 11212301].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.