ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (IPR033567)

Short name: CD38

Overlapping homologous superfamilies


Family relationships


CD38 is involved in synthesizing the second messagers cyclic ADP-ribose (cADPR) and nicotinate-adenine dinucleotide phosphate (NAADP) [PMID: 11829748, PMID: 10891341]. NAADP and cADPR are calcium messengers in a wide variety of cells.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0050135 NAD(P)+ nucleosidase activity
GO:0003953 NAD+ nucleosidase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.