Pathways & interactions
Short name: BECN2
Overlapping homologous superfamilies
- Atg6/Beclin (IPR007243)
- Beclin-2 (IPR032912)
Beclin-2 (BECN2) functions in autophagy and interacts with class III PI3K complex components and Bcl-2. It also functions in an additional lysosomal degradation pathway: it is required for ligand-induced endolysosomal degradation of several G protein-coupled receptors (GPCRs) through its interaction with GASP1 [PMID: 23954414].
- PTHR12768:SF5 (PTHR12768:SF5)