Beclin-2 (IPR032912)

Short name: BECN2

Overlapping homologous superfamilies


Family relationships


Beclin-2 (BECN2) functions in autophagy and interacts with class III PI3K complex components and Bcl-2. It also functions in an additional lysosomal degradation pathway: it is required for ligand-induced endolysosomal degradation of several G protein-coupled receptors (GPCRs) through its interaction with GASP1 [PMID: 23954414].

GO terms

Biological Process

GO:1990172 G protein-coupled receptor catabolic process
GO:0006914 autophagy

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.