Plastin-1 (IPR030235)

Short name: PLS1

Overlapping homologous superfamilies

Family relationships


Plastin-1 is an actin-bundling protein of the microvilli and stereocilia [PMID: 22114352, PMID: 19321664]. It is the most abundant actin-bundling protein of stereocilia. Mutations in the human PLS1 gene may be associated with relatively mild and progressive forms of hearing loss [PMID: 25124451].

GO terms

Biological Process

GO:0051017 actin filament bundle assembly

Molecular Function

GO:0051015 actin filament binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.