Pathways & interactions
Short name: PLS1
Overlapping homologous superfamilies
- CH domain superfamily (IPR036872)
- Fimbrin/Plastin (IPR039959)
- Plastin-1 (IPR030235)
Plastin-1 is an actin-bundling protein of the microvilli and stereocilia [PMID: 22114352, PMID: 19321664]. It is the most abundant actin-bundling protein of stereocilia. Mutations in the human PLS1 gene may be associated with relatively mild and progressive forms of hearing loss [PMID: 25124451].
- PTHR19961:SF27 (PTHR19961:SF27)