Bis(5'-adenosyl)-triphosphatase ENPP4 (IPR029879)

Short name: ENPP4

Overlapping homologous superfamilies

Family relationships


Ectonucleotide pyrophosphatase/phosphodiesterase family member 4 (ENPP4), also known as bis(5'-adenosyl)-triphosphatase, has a role in stimulating platelet aggregation and secretion. This procoagulant enzyme hydrolases diadenosine triphosphate Ap3A into AMP and ADP, providing a source of ADP necessary to sustain the clotting reaction at the site of the growing thrombus [PMID: 22995898].

GO terms

Biological Process

GO:0030194 positive regulation of blood coagulation

Molecular Function

GO:0047710 bis(5'-adenosyl)-triphosphatase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.