Pathways & interactions
Short name: Stathmin-3
Overlapping homologous superfamilies
- Stathmin superfamily (IPR036002)
- Stathmin family (IPR000956)
- Stathmin-3 (IPR028835)
Stathmin is a tubulin-binding protein involved in the control of MT assembly and dynamics [PMID: 17029844]. The related stathmin-like family members include super cervical ganglion protein 10 (SCG10), SCG10-like protein (SCLIP), and RB3 [PMID: 11278715].
SCG10-like protein (also known as stathmin-3 or Sclip) exhibits microtubule-destabilising activity, which is antagonised by Stat3, a member of the signal transducer and activator of transcription (STAT) family [PMID: 16401721]. It may have a role in regulating neuronal morphology and structural plasticity [PMID: 17135267, PMID: 22577147].
- PTHR10104:SF17 (PTHR10104:SF17)