Voltage gated sodium channel type 4, subunit alpha B (IPR028817)

Short name: Na_channel_a4suB

Overlapping homologous superfamilies


Family relationships


Genome-wide duplication event plays an important part in evolution of the SCNA (sodium channel alpha-subunit) gene family. The number of SCNA genes encoding Nav1 proteins in mammals and teleosts (fish) are similar -eight versus nine, respectively. They code for transmembrane Nav1 proteins that allow the sodium influx required for action potential generation in excitable cells [PMID: 16830092].

This entry represents sodium channel protein type 4 subunit alpha B (scn4ab) from fish [PMID: 16830092].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.