Adenylyl cyclase-associated protein CAP2 (IPR028418)

Short name: CAP2

Overlapping homologous superfamilies


Family relationships


This entry represents the adenylyl cyclase-associated protein 2 (CAP2) from vertebrates [PMID: 7962207]. It shares around 64% amino acid identity with CAP1, which regulates the actin cytoskeleton, cofilin function, and cell adhesion [PMID: 23737525]. Like CAP1, CAP2 contains a C-terminal actin-binding domain that may regulate actin remodelling in response to cellular signals and is required for normal cellular morphology, cell division, growth and locomotion in eukaryotes [PMID: 7890691]. However, the function of CAP2 is still not clear.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.