Zinc finger protein PLAGL1 (IPR027770)

Short name: PLAGL1

Overlapping homologous superfamilies


Family relationships



PLAG1, PLAGL1 and PLAGL2 constitute a family of zinc finger proteins that recognise DNA and/or RNA. This entry represents PLAGL1 (pleiomorphic adenoma-like protein 1), also known as ZAC, which shows weak transcriptional activatory activity [PMID: 9722527]. PLAGL1 is a transcriptional regulator of the type 1 receptor for pituitary adenylate cyclase-activating polypeptide [PMID: 18299245]. It has antiproliferative properties [PMID: 9671765, PMID: 9184226].

GO terms

Biological Process

GO:0006357 regulation of transcription by RNA polymerase II

Molecular Function

GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.