Vacuolar protein sorting-associated protein 13, N-terminal domain (IPR026854)

Short name: VPS13_N

Overlapping homologous superfamilies


Domain relationships



Although mutations in the full-length vacuolar protein sorting 13A (VPS13A) protein in vertebrates lead to the disease of chorea-acanthocytosis, the exact function of any of the regions within the protein is not yet known. This domain is the proposed leucine zipper at the N terminus of VPS13A and related proteins. The full-length protein is a transmembrane protein with a presumed role in vesicle-mediated sorting and intracellular protein transport [PMID: 17196930].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.