Domain

PGF-CTERM archaeal protein-sorting signal (IPR026371)

Short name: PGF_CTERM

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This entry represents a strictly archaeal putative protein-sorting motif, PGF-CTERM. It is the (predicted) recognition sequence for an exosortase homologue, archaeosortase. In some archaea, up to fifty proteins have this domain as their C-terminal region, usually preceded by a Thr-rich region likely to be heavily glycosylated. The removal of this sorting signal may be associated with a C-terminal prenyl group modification in the halobacterial major cell surface glycoprotein, an S-layer protein [PMID: 22037399].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
TIGRFAMs