NAD(P) transhydrogenase, alpha subunit (IPR026255)

Short name: NADP_transhyd_a

Overlapping homologous superfamilies

Family relationships



NAD(P) transhydrogenase (EC:, a tetramer composed of 2 alpha and 2 beta subunits, is an integral membrane protein that couples the proton transport across the membrane to the reversible transfer of hydride ion equivalents between NAD and NADP. This family is the is the alpha subunit. An alternate name is pyridine nucleotide transhydrogenase alpha subunit. The N-terminal region is homologous to alanine dehydrogenase. In some species, such as Rhodospirillum rubrum, the alpha chain is replaced by two shorter chains, both with some homology to the full-length alpha chain modelled here. These score below the trusted cut-off.

GO terms

Biological Process

GO:0055114 oxidation-reduction process
GO:1902600 proton transmembrane transport

Molecular Function

GO:0008746 NAD(P)+ transhydrogenase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.