S-receptor-like serine/threonine-protein kinase (IPR024171)

Short name: SRK-like_kinase

Overlapping homologous superfamilies


Family relationships



Plant S-receptor kinase-like genes have diverse functions in cell signalling, development, stress responses and host-pathogen defence responses [PMID: 12142267].

This entry contains receptor-like kinases, including S-locus receptor kinase (SRK). SRK is the female determinant of the self-incompatibility (SI) response in Brassica [PMID: 1681543, PMID: 10706292]. Flowering plants apply a self-incompatibility mechanism to prevent inbreeding and thereby increase genetic diversity [PMID: 12831470]. In most flowering plants, SI systems are controlled by a single multi-allelic locus termed the S-locus. Other members of this group do not play a role in SI [PMID: 8819313], and some members are from self-compatible plants such as Oryza sativa (Rice) and Arabidopsis thaliana (Mouse-ear cress), neither of which possess the SI response. P93068 and O23743 from Brassica oleracea (Wild cabbage), as well as O81905 from A. thaliana, are reported to possibly have overlapping roles in both defence and development [PMID: 9014364, PMID: 11814694].

The proteins in this family contain an extracellular D-mannose-binding lectin domain (IPR001480), an S-locus glycoprotein family domain (IPR000858), a PAN domain, and an intracellular kinase domain (IPR000719).

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0004674 protein serine/threonine kinase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.