Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase (IPR023709)

Short name: Guo-5TP_3DP_PyrP

Overlapping homologous superfamilies


Family relationships


Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the "stringent response", an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase (GppA), also known as guanosine pentaphosphate phosphohydrolase, catalyses the conversion of pppGpp to ppGpp.

GO terms

Biological Process

GO:0015974 guanosine pentaphosphate catabolic process

Molecular Function

GO:0008894 guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.