Family

dITP/XTP pyrophosphatase (IPR020922)

Short name: dITP/XTP_pyrophosphatase

Overlapping homologous superfamilies

Family relationships

Description

This entry represents a family of nucleoside-triphosphatases that hydrolyse non-standard nucleotides such as deoxyinosine triphosphate (dITP) and xanthosine triphosphate (XTP). It has been suggested that they may function as part of a preemptive DNA repair system by excluding non-standard purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions [PMID: 17090528].

GO terms

Biological Process

GO:0009143 nucleoside triphosphate catabolic process

Molecular Function

GO:0017111 nucleoside-triphosphatase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
HAMAP