Binding Site

Aminotransferase class-V, pyridoxal-phosphate binding site (IPR020578)

Short name: Aminotrans_V_PyrdxlP_BS


Aminotransferases share certain mechanistic features with other pyridoxal- phosphate dependent enzymes, such as the covalent binding of the pyridoxal- phosphate group to a lysine residue. On the basis of sequence similarity, these various enzymes can be grouped [PMID: 8482384] into subfamilies. This entry represents the class V aminotransferases and the related, though functionally distinct, cysteine desulfurases.

This signature represents a conserved region surrounding the lysine residue that binds the pyridoxal-phosphate [PMID: 8482384].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns