RNA polymerase II elongation factor ELL, N-terminal (IPR019464)

Short name: ELL_N

Overlapping homologous superfamilies


Domain relationships



This entry represents the N-terminal domain of EEL.

ELL is a family of RNA polymerase II elongation factors. It is bound stably to elongation-associated factors 1 and 2, EAFs, and together these act as a strong regulator of transcription activity. by direct interaction with Pol II. ELL binds to pol II on its own but the affinity is greatly increased by the cooperation of EAF [PMID: 17150956]. Some members carry an occludin domain (IPR010844) just downstream. There is no Saccharomyces cerevisiae (Baker's yeast) member.

GO terms

Biological Process

GO:0006368 transcription elongation from RNA polymerase II promoter

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0008023 transcription elongation factor complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.